KU Leuven hosts three VIB research centers dispersed over various locations.

The VIB-KU Leuven Center for Cancer Biology and the VIB-KU Leuven Center for Brain & Disease Research are situated on the campus Gasthuisberg in Leuven. The Bioimaging Core, Nucleomics Core and Metabolomics Core are also housed in this building.

The VIB-KU Leuven Center for Microbiology is spread over three different locations: Campus Arenberg, the Bio Incubator in Leuven and the Rega Institute on the campus Gasthuisberg.