Metabolomics Expertise Center

All living organisms need to sustain their growth and survival. To do this, nutrients (sugars, amino acids, fatty acids, etc) are chemically reorganized within the organism on the cellular level. These nutrients undergo a series of biochemical and molecular changes carried out by enzymes, resulting in the generation of energy or essential building blocks, whatever is needed to cope with the demand. 

Bart Ghesquière

Expert Technologist
Associate Professor KU Leuven since 2016
VIB Group Leader since 2014
Visiting Postdoc: Univ. of Delaware, Delaware, US, 2013
Postdoc: Vesalius Research Center, Leuven, Belgium, 2012-2014
Visiting Postdoc: NHLBI (NIH), Bethesda, US, 2011
Postdoc: Univ. Ghent, Ghent, Belgium, 2008-2011

Research areas

Human diseases Cancer Biology

Research focus

All living organisms need to sustain their growth and survival. To do this, nutrients (sugars, amino acids, fatty acids, etc) are chemically reorganized within the organism on the cellular level. These nutrients undergo a series of biochemical and molecular changes carried out by enzymes, resulting in the generation of energy or essential building blocks, whatever is needed to cope with the demand. These molecular changes are organized in a complex network of biochemical reactions that is highly interconnected, similar to a roadmap where we can distinguish main roads from secondary ones and as well, the amount of possibilities to go from A to B is endless. Understanding how these nutrients go through this roadmap and to what extent critical roads are used, is the Holy Grail in biochemical research.

​​​​​​​Metabolism describes the whole of enzymatic and biochemical reactions occurring inside and outside the cellular environment. Understanding how this 'engine' of reactions works and more importantly, understanding this dynamic network of biochemical reactions alters during specific conditions and diseases, provides a powerful tool for the development of novel drug strategies, treatment, diagnostics, etc.

Publications

To showcase the world-class scientific research of the Ghesquière Group, you can discover their scientific papers in more detail.

Jobs

We are always on the lookout for highly motivated colleagues to join our team. If you are interested to work on single-cell regulatory genomics - computational or experimental, please contact us.

Team 

The Ghesquière Group can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority. 

Events

To stay up to date in rapidly developing fields, scientists regularly interact with (international) colleagues. Conferences and other (scientific) events are an excellent way to facilitate such a continent-spanning knowledge exchange.