Contemporary proteomics for addressing the dynamics of proteomes.


Kris Gevaert

Deputy Science Director
Associate Department Director since 2014
Science Advisor of the VIB Proteomics Core since 2015
Acting Department Director 2010-2014
VIB Group leader since 2005
Postdoc.: Univ. of Ghent, Ghent, Belgium, 2000-2004
PhD: Univ. of Ghent, Ghent, Belgium, 2000

Research areas

Cell Biology Medical biotechnology Structural biology Systems biology

Research Focus

Triggered by challenging biomedical and biological research questions, we introduce technologies for studying the diverse aspects of proteomes by means of mass spectrometry. We focus on the analysis of protein modifications such as processing and master the enrichment of protein N-terminal peptides, which report such processing events. These N-terminal peptides are also the best proxies for co-translational events occurring on nascent protein chains. In this respect, we study the N-terminal acetyltransferases that steer alpha-N-terminal protein acetylation in different model systems, including disease models. 

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