The interests of the Loris group encompass the broad area of structure-function relationships in proteins. Our scientific questions relate to how proteins function in a cell, with a special interest on functional intrinsic disorder and dynamics. Via an integrative approach to structural biology, we unravel the molecular mechanisms that underlie the functions of IDPs in bacteria and plants. We understand at the molecular level novel and poorly understood principles that govern macromolecular recognition such as folding upon binding and fuzzy recognition.
Research areas
Structural biology MicrobiologyResearch topics
Research Focus
The focus of our research is on proteins and their mechanisms of action, but at the same time aims to resolve two fundamental biological questions. The first one is: how do toxin-antitoxin modules contribute to the bacterial stress response and persistence? The second one is: how does SOG1 co-ordinates the DNA damage response in plants and links it to cell cycle progress? What are the macromolecular partners of SOG1 and how do SOG1 and ts partners co-operate to control a large variety of target genes?
Publication
To showcase the world-class scientific research of the Remy Loris Lab, you can discover their scientific papers in more detail.
Jobs
We are always on the lookout for highly motivated colleagues to join our team. If you are interested, please contact us.
Team
The Remy Loris Lab can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority.
Events
To stay up to date in rapidly developing fields, scientists regularly interact with (international) colleagues. Conferences and other (scientific) events are an excellent way to facilitate such a continent-spanning knowledge exchange.