The Lim lab studies the metabolic and transcriptomic programmes that shape neuronal diversity and circuit assembly in the developing mammalian cortex.
We are interested to define at single-cell resolution the metabolic and transcriptomic programmes that shape neuronal diversity and circuit assembly in the developing mammalian cortex.
Our research focuses primarily on GABAergic cortical neurons since they are one of the most diverse cell types in the brain and play multifaceted roles in controlling principal pyramidal neurons and fine-tune network computation. We employ an interdisciplinary approach to our work that combines mouse genetics, virus tracing, cell fate-mapping, metabolomics, and single-cell RNA sequencing, with cutting-edge imaging techniques and bioinformatics to define how developmental programmes influence cortical circuit formation.
To showcase the world-class scientific research of the Lynette Lim Lab, you can discover their scientific papers in more detail.
We are always on the lookout for highly motivated colleagues to join our team. If you are interested, please contact us by applying for the job(s) below.
The Lynette Lim Lab can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority.
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