VIB Labs

Publications

To showcase the world-class scientific research of the Jan Steyaert Lab, you can discover their scientific papers in more detail.

All our publications

Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site.

Brams M, Govaerts C, Kambara K, Price K, Spurny R, Gharpure A, Pardon E, Evans G, Bertrand D, Lummis S, Hibbs R, Steyaert J, Ulens C

10.7554/eLife.51511

Nanobody-enabled monitoring of kappa opioid receptor states.

Che T, English J, Krumm B, Kim K, Pardon E, Olsen R, Wang S, Zhang S, Diberto J, Sciaky N, Carroll F, Steyaert J, Wacker D, Roth B

10.1038/s41467-020-14889-7

Modular transient nanoclustering of activated ß2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies.

Gormal R, Padmanabhan P, Kasula R, Bademosi A, Coakley S, Giacomotto J, Blum A, Joensuu M, Wallis T, Lo H, Budnar S, Rae J, Ferguson C, Bastiani M, Thomas W, Pardon E, Steyaert J, Yap A, Goodhill G, Hilliard M, Parton R, Meunier F

Proc Natl Acad Sci U S A

10.1073/pnas.2007443117

Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gai1.

Mcclelland L, Zhang K, Mou T, Johnston J, Yates-hansen C, Li S, Thomas C, Doukov T, Triest S, Wohlkönig A, Tall G, Steyaert J, Chiu W, Sprang S

10.1038/s41467-020-14943-4

Single-particle cryo-EM at atomic resolution.

Nakane T, Kotecha A, Sente A, Mcmullan G, Masiulis S, Brown P, Grigoras I, Malinauskaite L, Malinauskas T, Miehling J, Uchanski T, Yu L, Karia D, Pechnikova E, De J, Keizer J, Bischoff M, Mccormack J, Tiemeijer P, Hardwick S, Chirgadze D, Murshudov G, Aricescu A, Scheres S

10.1038/s41586-020-2829-0

A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations.

Paesmans J*, Martin E*, Deckers B, Berghmans M, Sethi R, Loeys Y, Pardon E, Steyaert J, Verstreken P, Galicia Diaz Santana C@, Versées W@

(* CoFirst, @ Corresponding)

10.7554/eLife.64922

Structural insight into the formation of lipoprotein-ß-barrel complexes.

Rodriguez-alonso R, Letoquart J, Nguyen V, Louis G, Calabrese A, Iorga B, Radford S, CHO S@, Remaut H@, COLLET J@

(@ Corresponding)

10.1038/s41589-020-0575-0

In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters.

Setyawati I, Stanek W, Majsnerowska M, Swier L, Pardon E, Steyaert J, Guskov A, Slotboom D

10.7554/eLife.64389

Discussions on the quality of antibodies are no reason to ban animal immunization.

Custers R@, Steyaert J

(@ Corresponding)

10.15252/embr.202051761

Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies.

Leemans M*, Galicia Diaz Santana C*, Deyaert E, Daems E, Krause L, Paesmans J, Pardon E, Steyaert J, Kortholt A, Sobott F, Klostermeier D, Versées W@

(* CoFirst, @ Corresponding)

10.1042/BCJ20190843