
Laboratory of Myeloid Cell Biology in Tissue Homeostasis and Regeneration
Our research focuses on the development and functional specialization of tissue-resident macrophages. We focus on the interactions between the macrophages and their tissue-specific niche.
Research areas
Immunology & inflammation Human diseases Computational biologyModel organisms
Research Focus
Our research focuses on the development and functional specialization of tissue-resident macrophages. We focus on the interactions between the macrophages and their tissue-specific niche and study the mutually beneficial cell-cell circuits between these cells. We take a modular view of tissues that integrates the resident macrophage as an essential component of each individual module. We focus most of our work on liver myeloid cells. We are particularly interested in: (i) identifying the transcription factors that imprint the liver-specific identities in each of the liver module partners, (ii) identifying the cell-cell circuits within the liver module and (iii) unraveling the role of each module partner in the maintenance of liver homeostasis and (iv) understanding what cell-cell circuits instruct liver regeneration and the formation of novel liver modules.

Publications
To showcase the world-class scientific research of the Martin Guilliams Lab, you can discover their scientific papers in more detail.
Jobs
We are always on the lookout for highly motivated colleagues to join our team. If you are interested, please contact us.
Team
The Martin Guilliams Lab can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority.
Events
To stay up to date in rapidly developing fields, scientists regularly interact with (international) colleagues. Conferences and other (scientific) events are an excellent way to facilitate such a continent-spanning knowledge exchange.