Structure and mechanism of protein complexes in immunity, inflammation, and cancer

We employ an integrative structural biology approach in conjunction with molecular interaction studies and cellular interrogation of the systems under study to elucidate the structural and mechanistic principles underlying the assembly, activation and pathophysiology of macromolecular complexes pivotal to inflammation, immunity, and cancer.

Savvas Savvides

Group Leader
VIB Group leader since 2015
Professor of Structural Biology
Professor: Ghent Univ., Ghent, Belgium, since 2005
EMBO Research Fellow: Vrije Universiteit Brussel, Belgium, 2002-2004
Postdoc: Washington Univ. School of Medicine, USA, 2000-2002
PhD: Cornell Univ., USA, 2000

Research areas

Structural biology Immunology & inflammation Medical biotechnology Human diseases

Research Focus

We employ integrative structural biology in conjunction with molecular interaction studies and in vitro and in vivo models, to elucidate the structural and mechanistic principles underlying the assembly and activation of macromolecular complexes pivotal to immunity, inflammation, and cancer. The cornerstone of our research approach lies in a rigorous and hypothesis-driven interrogation of the proteins and complexes under study, and is well nested in collaborations with leading academic research groups in Belgium and abroad, as well as partners from the biotechnology and pharmaceutical industry.

Funding

Publications

To showcase the world-class scientific research of the Savvas Savvides Lab, you can discover their scientific papers in more detail.

Jobs

We are always on the lookout for highly motivated colleagues to join our team. If you are interested, please contact us.

Team

The Savvas Savvides Lab can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority.

Events

To stay up to date in rapidly developing fields, scientists regularly interact with (international) colleagues. Conferences and other (scientific) events are an excellent way to facilitate such a continent-spanning knowledge exchange.