By investigating the livers of obese mice, the team of Prof. Charlotte Scott (VIB-UGent Center for Inflammation Research) has identified a new population of macrophages (immune cells) not present in healthy livers. These new cells were primarily located in the most damaged regions of the obese liver where they produce a protein that can be used to identify patients with severe fatty liver disease.
With a discovery that could rewrite the immunology textbooks, an international group of scientists, including the teams of Bart Lambrecht, Martin Guilliams, Hamida Hammad, and Charlotte Scott (all from the VIB-UGent Center for Inflammation Research) identified a new type of antigen-presenting immune cell.
VIB’s Charlotte Scott has been awarded an ERC starting grant worth €1.5 million. These renowned, highly competitive grants aim to help individual scientists and scholars to build their own teams and conduct pioneering research across all disciplines. Charlotte Scott will use the grant to pursue research tackling liver disease. She joins 53 other VIB ERC grantees.