About

Inhalable biologics to control respiratory infections

The main goal of this project is to come up with a radically different approach to control influenza. The general aim is to create biologicals that will be applied locally to treat and/or prevent influenza. The team will focus on the following specific goals:

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Development of a pan-influenza A neutralizing biological that will be effective against all influenza A strains and can be used every season and during global outbreaks.

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Generation of a stable cell line to produce the anti-influenza biologicals compliant with industrial production guidelines.

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Creation of a formulation that allows nebulization and hence local delivery of the biological in the airways.

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Execution of a cost-effectiveness study of the proposed biological-based solution with a focus on the prophylactic treatment in the elderly.